News Type: Research
To Track Environmental Impact on Genome, Don’t Forget the “Epi” in Genetics Research
In a review article published April 5 in the New England Journal of Medicine, scientist Andrew Feinberg, M.D., calls for more integration between two fields of DNA-based research: genetics and epigenetics.
Why do some athletes choke under pressure? The answer lies deep in the brain
Olympians most likely to bring home the gold are those who find a way to stay focused, even when the stakes are high.
Lights, camera, action! New endomicroscopic probes visualize living animal cell activity
Johns Hopkins researchers report they have developed two new endoscopic probes that significantly sharpen the technology’s imaging resolution and permit direct observation of fine tissue structures and cell activity in small organs in sheep, rats, and mice.
Spinning for the win: Repetition helps Olympians stay oriented
Kathleen Cullen explains why years of practice allow elite athletes to train their brains so they can stay on balance after elaborate maneuvers.
Hopkins lab develops arrhythmia treatment
Natalia Trayanova and her team of scientists and engineers, have developed personalized 3D computational heart models. But these aren’t just the average, stagnant 3D models. These computational models can show a heart in rhythm.
New Johns Hopkins center aims to unlock genetic mysteries of breast cancer
Biomedical engineer Joel Bader and cell biologist Andrew Ewald have joined forces to make sense of some of the genetic mysteries behind breast cancer.
Single Blood Test Screens for Eight Cancer Types
Researchers in the Johns Hopkins Kimmel Cancer Center and the Department of Biomedical Engineering have developed a single blood test that screens for eight common cancer types and helps identify the location of the cancer.
23andMe for Trees
Johns Hopkins researchers are part of an ambitious plan to fully sequence the coast redwood and giant sequoia genomes for the first time.
Upstarts: For Heartburn…And More
Patients with chronic acid reflux and other esophageal issues run an increased risk of cancer. A fiber-optic endomicroscope developed from research done by Xingde Li is likely to significantly improve diagnosis and treatment.
So Long, Trial and Error
Natalia Trayanova explains why computer simulations are key to the future for better health care.
Computer modeling offers insight into what causes sudden cardiac death
A team led by Johns Hopkins researchers constructed a powerful new computer model that replicates the biological activity within the heart that precedes sudden cardiac death.
Complete wheat: Scientists successfully piece together bread wheat genome
Nature reports that a team of six scientists—including three from Johns Hopkins University—has successfully mapped the genome of bread wheat, Triticum aestivum, a task that researchers around the world have been trying to crack for more than a decade.
Johns Hopkins-led team aims to turn computer systems into digital detectives
A Johns Hopkins University-led international team of scientists—supported by an $11-million, five-year U.S. Department of Defense grant—wants to streamline such investigations by developing algorithms for extracting relevant details from multi-modal data.
How the brain encodes our sense of direction
The latest publication by Kathleen Cullen, professor of biomedical engineering, is featured in the current issue of Nature Neuroscience, a special focus issue devoted to spatial cognition.
Developing the next generation of blood tests
Rene Vidal is part of a research effort that is working to make the average blood test more convenient.
Salzberg and Timp among research collaboration to sequence the Redwood genome
Steven Salzberg and Winston Timp are among the researchers from Johns Hopkins collaborating with the University of California, Davis, and the Save the Redwoods League in an ambitious plan to fully sequence the coast redwood and giant sequoia genomes for the first time.
How does our brain function when we gamble?
Sridevi Sarma and her team conducted an experiment that let them peek into subjects' brains as they gambled.
Mapping the Brain, Neuron by Neuron
Researchers in the Center for Imaging Science have taken an early step towards mapping how all animal brains work.
Defining the ‘Gold Standard’
A team of Johns Hopkins computational scientists and cancer experts devised its own bioinformatics software to evaluate how well current strategies identify cancer-promoting mutations and distinguish them from benign mutations in cancer cells.
Using T-Cells to encourage tissue regeneration
Most people know immune cells as the first responders to trauma—killing bacteria, fungi, viruses and other invaders—but there is a hidden side, as well. Immune cells also repair the body. They are both killers and healers.
Reversing the Loss of Sight
A novel peptide and drug delivery system developed by a trio of Johns Hopkins researchers is closer to improving vision care for millions of people who suffer from degenerative retinal diseases.
Zbijewski Leads New Program for Imaging of Bone Health
Dr. Wojciech Zbijewski's research is breaking new ground in imaging technology and advancing the clinical understanding of conditions affecting the bones and joints.
Engineering the Immune System
Meld the best of immunology and the best of engineering and what do you have? The nascent field of immunoengineering.
How Randomness Helps Cancer Cells Thrive
In a research effort that merged genetics, physics and information theory, a team at the schools of medicine and engineering...
First fully artificial yeast genome has been designed
Working as part of an international research consortium, a multidisciplinary team at the Johns Hopkins University has completed the design phase for a fully synthetic yeast genome.
New Gene Sequencing Software Could Aid in Early Detection and Treatment of Cancer
Winston Timp, an assistant professor of biomedical engineering, supervised research on new computational software that determines if a human DNA sample includes an epigenetic add-on linked to cancer and other health conditions.
New Peptide Could Improve Treatment for Vision-Threatening Disease
Johns Hopkins researchers report that a new peptide holds promise for improving treatment for degenerative retinal diseases, such as age-related macular degeneration, diabetic macular edema and diabetic retinopathy. These vascular diseases often result in central vision loss as blood vessels grow into tissues at the back of the eye, where such growth should not occur.
Noninvasive Ultrasound Pulses Used to Precisely Tweak Rat Brain Activity
Jordan Green, associate professor of biomedical engineering, and his colleagues have figured out a noninvasive way to release and deliver concentrated amounts of a drug to the brain of rats in a temporary, localized manner using ultrasound.
Potentially Reversible Changes in Gene Control ‘Prime’ Pancreatic Cancer Cells to Spread
A multicenter team of researchers reports that a full genomic analysis of tumor samples from a small number of people who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence itself yet control how it operates confer survival advantages on subsets of pancreatic cancer cells. Those advantages, the researchers say, let such cancer cells thrive in organs like the liver and lungs, which receive a sugar-rich blood supply.
Michael Miller: Catching Alzheimer’s Early
Michael Miller, the Herschel and Ruth Sedar Professor of Biomedical Engineering and University Gilman Scholar, is analyzing MRI brain images of the elderly to unveil lurking signs of Alzheimer that cognitive tests cannot detect.