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News Type: Research

Machine learning helps scientists see how the brain adapts to different environments

Visualizing connections between nerve cells in the brain could yield insights into how our brains change with learning, aging, injury, and disease.

Whether physical exertion feels ‘easy’ or ‘hard’ may be due to dopamine levels, study suggests

Dopamine, a brain chemical long associated with pleasure, motivation and reward-seeking, also appears to play an important role in why exercise and other physical efforts feel “easy” to some people and exhausting to others, according to results of a study of people with Parkinson’s disease led by Johns Hopkins Medicine researchers.

Scientists complete 1st map of an insect brain

Researchers have completed the most advanced brain map to date, that of an insect, a landmark achievement in neuroscience that brings scientists closer to true understanding of the mechanism of thought.

Heart tissue heads to space to aid research on aging and impact of long spaceflights

Johns Hopkins Medicine researchers are collaborating with NASA to send human heart “tissue-on-a-chip” specimens into space as early as March. The project is designed to monitor the tissue for changes in heart muscle cells’ mitochondria (their power supply) and ability to contract in low-gravity conditions.

Can we trust AI?

From Alexa to a robot running amok in the movie 'M3GAN', artificial intelligence is part of everyday life and is capturing our imagination. Johns Hopkins AI expert Rama Chellappa helps us sort out fact from fiction, and whether we should embrace the 'AI spring'.

Research team creates statistical model to predict COVID-19 resistance

Researchers from Johns Hopkins have created and preliminarily tested what they believe may be one of the first models for predicting who has the highest probability of being resistant to COVID-19 in spite of exposure to SARS-CoV-2, the virus that causes it.

How cancer cells organize

There is a certain class of pediatric brain cancers that is “universally deadly,” with a median survival of 15 months and few, if any, viable treatment options. The key to combating these cancers might be in analyzing how the cells within tumor tissue—cancer cells, immune cells, and others—express genes and organize themselves spatially.

Johns Hopkins physicians and engineers search for AI program that accurately predicts risk of ‘ICU delirium’

An intensivist at Johns Hopkins Medicine, in collaboration with Johns Hopkins University engineering students, report they have developed artificial intelligence (AI) algorithms that can detect the early warning signs of delirium and can predict — at any time during an ICU stay — a high risk of delirium for a significant number of patients.

When grandpa can’t hear words at a noisy holiday gathering, too many brain cells may be firing at once

Johns Hopkins Medicine researchers say they found that old mice were less capable than young mice of “turning off” certain actively firing brain cells in the midst of ambient noise.

News Brief: Researchers capture 3D cellular dynamics across whole organism

A team of researchers from Johns Hopkins have shown that a new microscopy technique can capture dynamic 3D images of an entire zebrafish larvae while maintaining cellular resolution in all three dimensions.

New computer model tracks origin of cell changes that drive development

Scientists at Johns Hopkins Medicine say they have developed a computer model — dubbed quantitative fate mapping — that looks back in the developmental timeline to trace the origin of cells in a fully grown organism.

New Tools Map Seizures, Improve Epilepsy Treatment

Two new models could solve a problem that’s long frustrated millions of people with epilepsy and the doctors who treat them: how to find precisely where seizures originate to treat exactly that part of the brain.

Expert: It’s time to stop creating ‘superbugs’ in the lab

Johns Hopkins computational biologist Steven Salzberg says controversial Boston University study that created a potentially deadly form of the omicron coronavirus variant should never have happened.

Newly created protein a step toward preventing autoimmune disorders

Researchers design a protein that can activate and increase the number of specialized cells that can prevent the onset of autoimmune disorders.

Researchers find link between immune cells’ closest neighbors and survival time in patients with pancreatic cancer

Researchers from Johns Hopkins Medicine have discovered that the organization of different types of immune cells within pancreatic tumors is associated with how well patients with pancreatic cancer respond to treatment and how long they survive.

New study uncovers major cause of deadly heart arrhythmias

Fat inside the heart, a possible after effect of heart attacks, is a large player in the development of heart rhythm disturbances.

Johns Hopkins, Howard University Partner to Develop Tech for Neuro Disorders

Johns Hopkins University and Howard University are teaming up to develop medical devices to diagnosis, treat, and manage neurological disorders.

Vital tech with a fatal flaw

The pulse oximeter is now a staple in hospital rooms and personal medicine cabinets. But a major flaw in its design could prevent people of color from receiving the care they need.

News Brief: Fourteen students received NSF Graduate Research Fellowships

Fourteen students from the Johns Hopkins Department of Biomedical Engineering received an NSF Graduate Research Fellowship. The fellowship recognizes graduate...

Hopkins BME Cahan, Durr win Catalyst Awards

Two faculty Biomedical Engineering faculty members will receive 2022 Johns Hopkins Catalyst Awards. Patrick Cahan and Nicholas Durr were among...

From Blurry to Bright: AI Tech Helps Researchers Peer into the Brains of Mice

Johns Hopkins biomedical engineers have developed an artificial intelligence (AI) training strategy to capture images of mouse brain cells in...

AI predicts if and when someone will experience cardiac arrest

An algorithm built to assess scar patterns in patient heart tissue can predict potentially life-threatening arrhythmias more accurately than doctors can.

Johns Hopkins and Amazon collaborate to explore transformative power of AI

The new JHU + Amazon Initiative for Interactive AI will advance machine learning, computer vision, natural language understanding, and speech processing while increasing access to these technologies.

Johns Hopkins scientists contribute to first complete sequence of human genome

A group of Johns Hopkins University scientists has collaborated with more than 100 researchers around the world to assemble and analyze the first complete sequence of a human genome, two decades after the Human Genome Project produced the first draft.

New heart modeling method may help doctors pump the brakes on sudden cardiac death

Digital, personalized replicas of patients' hearts can help health care providers to better predict who will need implanted defibrillators over time.

Tissue Engineering: The Future is Here

Through advances in biomaterials, stem cell science, and more, researchers are moving tantalizingly close to regenerating damaged body parts, creating new organs, and equipping our existing tissues to fight off debilitating diseases.

New Color-Coded Test Quickly Reveals If Medical Nanoparticles Deliver Their Payload

Johns Hopkins Medicine researchers have developed a color-coded test that quickly signals whether newly developed nanoparticles deliver their cargo into target cells.

A stunning 3D map of blood vessels and cells in a mouse skull could help scientists make new bones

Johns Hopkins Medicine scientists have used glowing chemicals and other techniques to create a 3D map of the blood vessels and self-renewing “stem” cells that line and penetrate a mouse skull.

Sarma named a recipient of Thalheimer Fund Grant

Sridevi Sarma, associate professor in the Department of Biomedical engineering, and Khalil Husari, associate professor in the Department of Neurology, have received a technology development grant through the Louis B. Thalheimer Fund for Translational Research.

Startup founders from Johns Hopkins aim to stop spread of cancer

AbMeta Therapeutics, launched by biologist and Provost Denis Wirtz, bioengineer Jamie Spangler, and clinician Elizabeth Jaffee, will combine years of pioneering research to target metastasis.

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